Chromatography Supplies
Medchemexpress LLC PMX 205 Trifluoroacetate | 99.50% | 953.06 | 1 ML
PMX 205 Trifluoroacetate is a specific complement C5aR1 isoform antagonist. It is intended for research use only and not for sale to patients.
- Specific complement C5aR1 isoform antagonist.
- Purity of 99.50%.
- Molecular weight of 953.06.
- Chemical formula is C47H63F3N10O8.
- Appears as a white to off-white solid.
- Soluble in DMSO at ≥ 100 mg/mL.
- Shows significant inhibition of cell viability in MTT assays.
- Functions as an orally active, selective C5aR antagonist in rats.
- Reduces fibrillar plaque load in Tg2576 mice.
- Significantly reduces hyperphosphorylated tau in 3xTg mice.
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